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Abdulhadi Sale Kumurya
Sadiya Ashiru Auta
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Sadiya Ashiru Auta
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International Research Journal of Biochemistry and Biotechnology

Thyroid hormones parameters of patients with thyroid disorders attending special out-patient clinic at Murtala Muhammad Specialist Hospital, Kano, Nigeria

*Abdulhadi Sale Kumurya and Sadiya Ashiru Auta

*Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, P.M.B. 3011, Kano-Nigeria

Department of Biochemistry, Faculty of Basic Medical Science, Bayero University, P.M.B. 3011, Kano-Nigeria

Accepted 31 May, 2016.

Citation: Kumurya AS, Auta SA (2016). Thyroid hormones parameters of patients with thyroid disorders attending special out-patient clinic at Murtala Muhammad Specialist Hospital, Kano, Nigeria. International Research Journal of Biochemistry and Biotechnology, 3(1): 051-054.

 

Copyright: © 2016 Kumurya and Auta. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.

Abstract

Thyroid hormones, triiodothyronine (T3) and Thyroxin (T4), affect almost all metabolic activities of tissues and are produced under influence of the interior pituitary hormone, the thyroid stimulating hormone (TSH), which stimulates secretion of thyroid releasing hormone (TRH).  The present study was conducted to observe the effect of non-detectable levels of TSH on thyroid hormones, on the basis of gender and age.  A total of 88 patients (50 patients with hyperthyroidism and hypothyroidism and 33 healthy people as control) attending special out-patient clinic were involved in the study. Serums T3, T4 and TSH were measured using the commercially available kits (Abbot Laboratories) through Enzyme Immune Assay (EIA) technique (Roche Diagnostics GmbH). Analysis of data using SPSS software version 15.0 revealed that prevalence of thyroid disorders in the studied group was more among female population.  However, the disorders were not age dependent.  Most common conditions associated with sub-clinical hyperthyroidism.  As males are equally exposed to these environmental factors, hence further investigations are required to know why these factors affect females more than the males. In our opinion, TSH and FT4 are the most valuable indicators in assessing thyroid function in a healthy population and TSH and TT4 are the most meaningful in hyperthyroidism and hypothyroidism.

Keywords: Thyroid, Hyperthyroidism, Non-detectable TSH, Kano.