Dyslipidemia in pregnancy in a rural population in North India
Sunil Kumar, Gora Dadheech* and RC Gupta
Accepted 8 June, 2014.
Citation: Kumar S, Dadheech G, RC Gupta (2014). Dyslipidemia in pregnancy in a rural population in North India. International Research Journal of Biochemistry and Biotechnology, 1(1): 002-004.
Copyright: © 2014 Dadheech et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.
Physiologically, a female becomes almost a new person during pregnancy because of profound local and systemic changes initiated by conception which continue throughout pregnancy. Biochemical changes during pregnancy have been studied extensively, but mostly in urban populations. In this study we report changes in serum lipids and lipoproteins in rural pregnant women. The study was conducted on sixty pregnant women (20 each in 1st,2nd and 3rd trimester) from rural population. Biochemical investigations for accessing serum lipids were done on a fully automatic analyser (TrivitronNanolab 150) using standard kits. Serum triglycerides, serum total cholesterol, low density lipoprotein and very low density lipoprotein were found to be increased significantly (p<0.001) in sixty pregnant women as compared to twenty non-pregnant women from rural areas near Jaipur. Serum triglycerides were raised 2.7 fold in the third trimester of pregnancy as compared to non-pregnant women. Serum high density cholesterol was comparable in the two groups. This preliminary study underlines the need for investigating serum lipid changes in pregnancy in bigger rural samples in different parts of the country.
Keywords: Dyslipidemia, triglycerides, high density lipoproteins, low density lipoproteins, cholesterol, rural pregnant women, cardiovascular diseases